Class: pairwise gene to gene interaction

An interaction between two genes or two gene products. May be physical (e.g. protein binding) or genetic (between genes). May be symmetric (e.g. protein interaction) or directed (e.g. phosphorylation)

URI: http://w3id.org/biolink/vocab/PairwiseGeneToGeneInteraction

Mappings

Inheritance

• is_a: GeneToGeneAssociation - abstract parent class for different kinds of gene-gene or gene product to gene product relationships. Includes homology and interaction.
• mixin: PairwiseInteractionAssociation - An interaction at the molecular level between two physical entities

  Children

Used in

Fields

• pairwise gene to gene interaction.relation
  • Description: interaction relationship type
  • range: RelationshipType [required]
  • edge label: molecularly interacts with subsets: (translator_minimal)
  • Local
• association slot
  • Description: any slot that relates an association to another entity
  • range: string
  • inherited from: Association
• association type
  • Description: connects an association to the type of association (e.g. gene to phenotype)
  • range: OntologyClass
  • inherited from: Association
• category subsets: (translator_minimal)
  • Description: Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class. In a neo4j database this MAY correspond to the neo4j label tag
  • range: IriType*
  • inherited from: NamedThing
• description subsets: (translator_minimal)
  • Description: a human-readable description of a thing
  • range: NarrativeText
  • inherited from: NamedThing
• full name
  • Description: a long-form human readable name for a thing
  • range: LabelType
  • inherited from: NamedThing
• gene to gene association.object
  • Description: the object gene in the association. If the relation is symmetric, subject vs object is arbitrary. We allow a gene product to stand as proxy for the gene or vice versa
  • range: GeneOrGeneProduct [required]
  • inherited from: GeneToGeneAssociation
• gene to gene association.subject
  • Description: the subject gene in the association. If the relation is symmetric, subject vs object is arbitrary. We allow a gene product to stand as proxy for the gene or vice versa
  • range: GeneOrGeneProduct [required]
  • inherited from: GeneToGeneAssociation
• id subsets: (translator_minimal)
  • Description: A unique identifier for a thing. Must be either a CURIE shorthand for a URI or a complete URI
  • range: IdentifierType
  • inherited from: NamedThing
• pairwise interaction association.interacting molecules category
  • range: OntologyClass
  • inherited from: PairwiseInteractionAssociation
• iri subsets: (translator_minimal)
  • Description: An IRI for the node. This is determined by the id using expansion rules.
  • range: IriType
  • inherited from: NamedThing
• name subsets: (translator_minimal)
  • Description: A human-readable name for a thing
  • range: LabelType
  • inherited from: NamedThing
• negated
  • Description: if set to true, then the association is negated i.e. is not true
  • range: boolean
  • inherited from: Association
• node property
  • Description: A grouping for any property that holds between a node and a value
  • range: string
  • inherited from: NamedThing
• provided by
  • Description: connects an association to the agent (person, organization or group) that provided it
  • range: Provider
  • inherited from: Association
• publications
  • Description: connects an association to publications supporting the association
  • range: Publication*
  • inherited from: Association
• qualifiers
  • Description: connects an association to qualifiers that modify or qualify the meaning of that association
  • range: OntologyClass*
  • inherited from: Association
• related to
  • Description: A grouping for any relationship type that holds between any two things
  • range: NamedThing
  • inherited from: NamedThing
• systematic synonym
  • Description: more commonly used for gene symbols in yeast
  • range: LabelType
  • inherited from: NamedThing